5-MeO-DMT | Psychedelics Integration

Table of Contents

Psychedelics Integration does not encourage or condone any illegal activities, including but not limited to the use of illegal substances. This guide aims to inform and reduce harm, not to replace medical, psychological, or psychiatric diagnosis, treatment, or advice. Keep in mind that psychedelics work differently with everyone, due to many factors such as physical health, mental health, illnesses, set & setting and a mix of substances.

What is 5-MEO-DMT?

5-MeO-DMT (5-Methoxy-N, N-dimethyltryptamine) is a powerful psychedelic compound found in various plants and the secretions of various toads. It is chemically similar to DMT (N, N-dimethyltryptamine) but has distinct effects and a shorter duration. 5-MeO-DMT is known for its intense, short-lived, and often transformative psychedelic experiences. It primarily acts as a serotonin receptor agonist.

Incilius alvarius, often incorrectly referred to as Bufo alvarius or simply bufo, is a semi-aquatic amphibian found in the Sonoran Desert of Mexico and the Southwestern United States. The skin glands of this toad secrete over a dozen tryptamine derivatives, including bufotenin and 5-MeO-DMT (5-methoxy-dimethyltryptamine), though they do not produce DMT (N,N-dimethyltryptamine). Bufotenin and 5-MeO-DMT are two potent psychedelic compounds.

5-MeO-DMT street names:

Toad Venom
Incilius Alvarius
Colorado River Toad
Bufo Alvarius
Sakred
The God Molecule

What Does 5-MEO-DMT Look Like?

The substance can range from white to off-white or light brown. 5-MEO-DMT is usually found as a crystalline powder. The texture can vary from fine powder to more coarse crystals.

What Are the Experiences with 5-MEO-DMT?

The experience with 5-MeO-DMT is typically profound and short-lived, lasting around 15-20 minutes. Users often report a rapid onset of effects, a sensation of leaving their body or ego dissolution, and a merging with the universe or a sense of unity with all things. These experiences are often described as mystical, ego-obliterating, and transcendental, with users feeling a profound connection to the universe or a divine presence.

Additionally, because the effects set in quickly and intensely, it’s common for individuals to experience fear and panic, and the experience can be overwhelming and traumatic for some. During the experience, individuals may involuntarily make movements and produce sounds like screaming, singing, or crying, often without being aware of their actions.

What Are the Acute Effects of 5-MEO-DMT & How Long Do They Last?

Profound ego dissolution and a loss of sense of self.
Intense, vivid, and often ineffable mystical or spiritual experiences.
A strong sense of unity with the universe or a divine presence.
Altered perceptions of time, space, and reality.
Emotional release and catharsis.
Enhanced sensory perception, including visual and auditory distortions.

What Are the Benefits & Risks?

Benefits

Spiritual and Personal Insights: Many users report profound spiritual or personal insights, leading to increased self-awareness and personal growth.
Therapeutic Potential: 5-MeO-DMT is being explored for its therapeutic potential in treating conditions like depression, anxiety, and addiction.
Mystical Experiences: It can induce intense mystical experiences that some find meaningful and transformative.

Risks

Intensity: The intensity of the experience can be overwhelming and potentially distressing.
Unpredictability: Individual responses vary, and it can be difficult to predict the exact nature of the experience.
Physical Risks: 5-MeO-DMT can lead to rapid heart rate and elevated blood pressure, which may pose risks for individuals with heart conditions.
Mental Health: It may exacerbate or trigger mental health issues in some individuals.

Therapeutic Use of 5-MEO-DMT & Personal Growth

There has been already some research proving the positive effects of 5-MeO-DMT for:

Beckley Psytech sees in 5-MeO-DMT a big potential as a psychedelic therapy substance, thanks to its it’s very short-acting and very potent compound.

Personal Development & Growth
Many users of 5-MeO-DMT report experiences that they consider highly meaningful and transformative. These experiences can lead to personal growth, increased self-awareness, and a shift in one’s perspective on life and the universe.

Legality

The legal status of 5-MeO-DMT varies by country and region. In some places, it is classified as a controlled substance, while in others, it may be unregulated or decriminalized. In the United States, bufotenin and 5-MeO-DMT are classified as Schedule I substances, making their sale, possession, and use illegal. In the United Kingdom, both substances are similarly regulated as Class A drugs. Additionally, other European nations, such as Sweden, have classified these substances as controlled, placing them on their national lists of prohibited substances.

For more information, check out this overview of 5-MeO-DMT legality per country.

History & Statistics

5-MeO-DMT has a long history of use in indigenous shamanic practices, particularly in South America.

It gained popularity in Western psychedelic culture during the mid-20th century. Statistics on its use are limited due to its relatively recent emergence in mainstream consciousness and its legal status.

Myths Surrounding 5-MEO-DMT

Not LSD: 5-MeO-DMT is often confused with LSD, but they are entirely different substances with distinct effects.
Legal Status: Some people believe it is legal everywhere, which is not true; its legality varies worldwide.
Non-Psychoactive: Contrary to some myths, 5-MeO-DMT is a potent psychoactive compound with intense effects.
Safe for Everyone: Like all psychedelics, 5-MeO-DMT is not without risks, and its safety depends on individual factors and proper use. It should not be considered universally safe for all individuals.

It’s important to approach 5-MeO-DMT with caution and understand its effects and risks. Have you had an experience with 2C-B and need support to integrate it? Or do you plan on having one and want the best setting possible? Book a session with one of our coaches.