Psychedelics Integration does not encourage or condone any illegal activities, including but not limited to the use of illegal substances. This guide aims to inform and reduce harm, not to replace medical, psychological, or psychiatric diagnosis, treatment, or adviceKeep in mind that psychedelics work differently with everyone, due to many factors such as physical health, mental health, illnesses, set & setting and a mix of substances.


Tepezcohuite, also known as Mimosa tenuiflora or Mimosa hostilis or “Tree of Skin“, is a perennial shrub or tree native to the southeastern part of Mexico, Central America, and parts of South America. It’s renowned for its bark, which has been used for centuries by indigenous peoples for its healing properties. The tree can grow up to 8 meters tall and is characterized by its dark brown to gray bark, fern-like leaves, and small, white flowers.

Tepezcohuite, a revered member of the ancient lineage of sacred medicines, contains DMT. In northeastern Brazil, traditional practices involve using parts of the tree to create a psychoactive brew, known locally as Jurema or Yurema. This medicinal plant, with origins tracing back to the southern parts of Mexico and Guatemala, historically facilitated the Mayans in connecting with the spirits of their forebears.


Unlike other parts of the plant, the bark does not contain psychoactive substances that would lead to psychedelic experiences. However, the root bark of Mimosa tenuiflora contains significant amounts of DMT (N,N-Dimethyltryptamine), a powerful psychedelic compound.


  • Intense Visual Hallucinations: Users often report vivid, sometimes elaborate visual experiences, with intricate patterns, shapes, and colors.
  • Altered State of Consciousness: The experience can include a sense of time distortion, alterations in the perception of reality, and profound shifts in emotional and philosophical insights.
  • Spiritual Experiences: Some individuals report mystical or spiritual experiences, including feelings of unity with the universe, encounters with entities, or profound personal revelations.
  • Emotional Intensity: The emotional response can be intense and varied, ranging from euphoria to distress.

How tO use Tepezcohuite

In certain traditional and ceremonial contexts, particularly in northeastern Brazil, the root bark of Mimosa tenuiflora, which contains DMT, is prepared as part of a psychoactive decoction known as Jurema or Yurema. This preparation is often part of spiritual or religious ceremonies and is believed to facilitate mystical experiences or spiritual insight. The process typically involves:

  • Harvesting the root bark of the Mimosa tenuiflora tree.
  • Preparing a decoction by boiling the root bark in water for several hours to extract the psychoactive compounds.
  • The resulting liquid is then consumed within a ritualistic or ceremonial setting, often under the guidance of experienced practitioners.

Benefits & Risks

BenefitsWound healing.
Skin ailments.
Treatment of Skin Conditions.
Treating health issues, such as cough, bronchitis, vaginal infections, stomach ulcers, and pain.
RisksBurning and tingling sensation when topically used.
Fetal abnormalities or embryonic death when consuming fresh seeds. Do not consume it ig you are pregnant.

Therapeutic Use

While tepezcohuite has been used traditionally for centuries and is included in various modern skincare products, scientific research on its effectiveness and mechanisms is still limited.

Legality of Tepezcohuite

The plant is legal.

History & Stats

Tepezcohuite has a long history of traditional use, particularly among the indigenous communities of Mexico and Brazil, for its medicinal properties. The Mayans were known to use tepezcohuite bark to treat skin conditions and injuries. It was also utilized in traditional medicine for a variety of ailments, ranging from skin issues to coughs and gastrointestinal problems.

It’s important to approach Tepezcohuite with caution and understand its effects and risks. Have you had an experience with Ayahuasca and need support to integrate it? Or do you plan on having one and want the best setting possible? Book a session with one of our coaches.

Our Psychedelic Coaches Integrating Tepezcohuite Experiences